Reduced signal for polygenic adaptation of height in UK Biobank

Several recent papers have reported strong signals of selection on European polygenic height scores. These analyses used height effect estimates from the GIANT consortium and replication studies. Here, we describe a new analysis based on the the UK Biobank (UKB), a large, independent dataset. We fin...

Descripción completa

Detalles Bibliográficos
Autores principales: Berg, Jeremy J, Harpak, Arbel, Sinnott-Armstrong, Nasa, Joergensen, Anja Moltke, Mostafavi, Hakhamanesh, Field, Yair, Boyle, Evan August, Zhang, Xinjun, Racimo, Fernando, Pritchard, Jonathan K, Coop, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428572/
https://www.ncbi.nlm.nih.gov/pubmed/30895923
http://dx.doi.org/10.7554/eLife.39725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428572/
https://www.ncbi.nlm.nih.gov/pubmed/30895923
http://dx.doi.org/10.7554/eLife.39725

Ejemplares similares