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Reduced signal for polygenic adaptation of height in UK Biobank
Several recent papers have reported strong signals of selection on European polygenic height scores. These analyses used height effect estimates from the GIANT consortium and replication studies. Here, we describe a new analysis based on the the UK Biobank (UKB), a large, independent dataset. We fin...
Autores principales: | Berg, Jeremy J, Harpak, Arbel, Sinnott-Armstrong, Nasa, Joergensen, Anja Moltke, Mostafavi, Hakhamanesh, Field, Yair, Boyle, Evan August, Zhang, Xinjun, Racimo, Fernando, Pritchard, Jonathan K, Coop, Graham |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428572/ https://www.ncbi.nlm.nih.gov/pubmed/30895923 http://dx.doi.org/10.7554/eLife.39725 |
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