Reduced signal for polygenic adaptation of height in UK Biobank

Several recent papers have reported strong signals of selection on European polygenic height scores. These analyses used height effect estimates from the GIANT consortium and replication studies. Here, we describe a new analysis based on the the UK Biobank (UKB), a large, independent dataset. We fin...

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Bibliografiska uppgifter
Huvudupphovsmän: Berg, Jeremy J, Harpak, Arbel, Sinnott-Armstrong, Nasa, Joergensen, Anja Moltke, Mostafavi, Hakhamanesh, Field, Yair, Boyle, Evan August, Zhang, Xinjun, Racimo, Fernando, Pritchard, Jonathan K, Coop, Graham
Materialtyp: Online Artikel Text
Språk:English
Publicerad: eLife Sciences Publications, Ltd 2019
Ämnen:
Evolutionary Biology
Länkar:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428572/
https://www.ncbi.nlm.nih.gov/pubmed/30895923
http://dx.doi.org/10.7554/eLife.39725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428572/
https://www.ncbi.nlm.nih.gov/pubmed/30895923
http://dx.doi.org/10.7554/eLife.39725

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