Methylome-wide association findings for major depressive disorder overlap in blood and brain and replicate in independent brain samples

We present the first large-scale methylome-wide association studies (MWAS) for major depressive disorder (MDD) to identify sites of potential importance for MDD etiology. Using a sequencing-based approach that provides near-complete coverage of all 28 million common CpGs in the human genome, we assa...

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Detalles Bibliográficos
Autores principales: Aberg, Karolina A., Dean, Brian, Shabalin, Andrey A., Chan, Robin F., Han, Laura K.M., Zhao, Min, van Grootheest, Gerard, Xie, Lin Y., Milaneschi, Yuri, Clark, Shaunna L., Turecki, Gustavo, Penninx, Brenda W.J.H., van den Oord, Edwin J.C.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428621/
https://www.ncbi.nlm.nih.gov/pubmed/30242228
http://dx.doi.org/10.1038/s41380-018-0247-6

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