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Effective and Reliable Framework for Lung Nodules Detection from CT Scan Images

Lung cancer is considered more serious among other prevailing cancer types. One of the reasons for it is that it is usually not diagnosed until it has spread and by that time it becomes very difficult to treat. Early detection of lung cancer can significantly increase the chances of survival of a ca...

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Autores principales: Khan, Sajid Ali, Hussain, Shariq, Yang, Shunkun, Iqbal, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428823/
https://www.ncbi.nlm.nih.gov/pubmed/30899052
http://dx.doi.org/10.1038/s41598-019-41510-9
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author Khan, Sajid Ali
Hussain, Shariq
Yang, Shunkun
Iqbal, Khalid
author_facet Khan, Sajid Ali
Hussain, Shariq
Yang, Shunkun
Iqbal, Khalid
author_sort Khan, Sajid Ali
collection PubMed
description Lung cancer is considered more serious among other prevailing cancer types. One of the reasons for it is that it is usually not diagnosed until it has spread and by that time it becomes very difficult to treat. Early detection of lung cancer can significantly increase the chances of survival of a cancer patient. An effective nodule detection system can play a key role in early detection of lung cancer thus increasing the chances of successful treatment. In this research work, we have proposed a novel classification framework for nodule classification. The framework consists of multiple phases that include image contrast enhancement, segmentation, optimal feature extraction, followed by employment of these features for training and testing of Support Vector Machine. We have empirically tested the efficacy of our technique by utilizing the well-known Lung Image Consortium Database (LIDC) dataset. The empirical results suggest that the technique is highly effective for reducing the false positive rates. We were able to receive an impressive sensitivity rate of 97.45%.
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spelling pubmed-64288232019-03-28 Effective and Reliable Framework for Lung Nodules Detection from CT Scan Images Khan, Sajid Ali Hussain, Shariq Yang, Shunkun Iqbal, Khalid Sci Rep Article Lung cancer is considered more serious among other prevailing cancer types. One of the reasons for it is that it is usually not diagnosed until it has spread and by that time it becomes very difficult to treat. Early detection of lung cancer can significantly increase the chances of survival of a cancer patient. An effective nodule detection system can play a key role in early detection of lung cancer thus increasing the chances of successful treatment. In this research work, we have proposed a novel classification framework for nodule classification. The framework consists of multiple phases that include image contrast enhancement, segmentation, optimal feature extraction, followed by employment of these features for training and testing of Support Vector Machine. We have empirically tested the efficacy of our technique by utilizing the well-known Lung Image Consortium Database (LIDC) dataset. The empirical results suggest that the technique is highly effective for reducing the false positive rates. We were able to receive an impressive sensitivity rate of 97.45%. Nature Publishing Group UK 2019-03-21 /pmc/articles/PMC6428823/ /pubmed/30899052 http://dx.doi.org/10.1038/s41598-019-41510-9 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Khan, Sajid Ali
Hussain, Shariq
Yang, Shunkun
Iqbal, Khalid
Effective and Reliable Framework for Lung Nodules Detection from CT Scan Images
title Effective and Reliable Framework for Lung Nodules Detection from CT Scan Images
title_full Effective and Reliable Framework for Lung Nodules Detection from CT Scan Images
title_fullStr Effective and Reliable Framework for Lung Nodules Detection from CT Scan Images
title_full_unstemmed Effective and Reliable Framework for Lung Nodules Detection from CT Scan Images
title_short Effective and Reliable Framework for Lung Nodules Detection from CT Scan Images
title_sort effective and reliable framework for lung nodules detection from ct scan images
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428823/
https://www.ncbi.nlm.nih.gov/pubmed/30899052
http://dx.doi.org/10.1038/s41598-019-41510-9
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