First clinical case of KPC-3–producing Klebsiella michiganensis in Europe

Klebsiella michiganensis is a newly emerging human pathogen. We describe a case of bloodstream infection in an immunocompromised patient. The pathogen was repeatedly isolated from blood and one rectal swab, and was identified using routine standard procedures. Further investigations revealed that th...

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Autores principales: Seiffert, S.N., Wüthrich, D., Gerth, Y., Egli, A., Kohler, P., Nolte, O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
New Microbes in Human
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428935/
https://www.ncbi.nlm.nih.gov/pubmed/30949345
http://dx.doi.org/10.1016/j.nmni.2019.100516
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author Seiffert, S.N.
Wüthrich, D.
Gerth, Y.
Egli, A.
Kohler, P.
Nolte, O.
author_facet Seiffert, S.N.
Wüthrich, D.
Gerth, Y.
Egli, A.
Kohler, P.
Nolte, O.
author_sort Seiffert, S.N.
collection PubMed
description Klebsiella michiganensis is a newly emerging human pathogen. We describe a case of bloodstream infection in an immunocompromised patient. The pathogen was repeatedly isolated from blood and one rectal swab, and was identified using routine standard procedures. Further investigations revealed that the K. michiganensis was multidrug resistant, carrying a plasmid harbouring a Klebsiella pneumoniae carbapenemase (KPC)-3 carbapenemase gene. This plasmid has been frequently encountered in K. pneumoniae isolates in Europe but has never been described in K. michiganensis.
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spelling pubmed-64289352019-04-04 First clinical case of KPC-3–producing Klebsiella michiganensis in Europe Seiffert, S.N. Wüthrich, D. Gerth, Y. Egli, A. Kohler, P. Nolte, O. New Microbes New Infect New Microbes in Human Klebsiella michiganensis is a newly emerging human pathogen. We describe a case of bloodstream infection in an immunocompromised patient. The pathogen was repeatedly isolated from blood and one rectal swab, and was identified using routine standard procedures. Further investigations revealed that the K. michiganensis was multidrug resistant, carrying a plasmid harbouring a Klebsiella pneumoniae carbapenemase (KPC)-3 carbapenemase gene. This plasmid has been frequently encountered in K. pneumoniae isolates in Europe but has never been described in K. michiganensis. Elsevier 2019-02-23 /pmc/articles/PMC6428935/ /pubmed/30949345 http://dx.doi.org/10.1016/j.nmni.2019.100516 Text en © 2019 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle New Microbes in Human
Seiffert, S.N.
Wüthrich, D.
Gerth, Y.
Egli, A.
Kohler, P.
Nolte, O.
First clinical case of KPC-3–producing Klebsiella michiganensis in Europe
title First clinical case of KPC-3–producing Klebsiella michiganensis in Europe
title_full First clinical case of KPC-3–producing Klebsiella michiganensis in Europe
title_fullStr First clinical case of KPC-3–producing Klebsiella michiganensis in Europe
title_full_unstemmed First clinical case of KPC-3–producing Klebsiella michiganensis in Europe
title_short First clinical case of KPC-3–producing Klebsiella michiganensis in Europe
title_sort first clinical case of kpc-3–producing klebsiella michiganensis in europe
topic New Microbes in Human
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428935/
https://www.ncbi.nlm.nih.gov/pubmed/30949345
http://dx.doi.org/10.1016/j.nmni.2019.100516
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