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Identification of Leishmania major UDP-Sugar Pyrophosphorylase Inhibitors Using Biosensor-Based Small Molecule Fragment Library Screening

Leishmaniasis is a neglected disease that is caused by different species of the protozoan parasite Leishmania, and it currently affects 12 million people worldwide. The antileishmanial therapeutic arsenal remains very limited in number and efficacy, and there is no vaccine for this parasitic disease...

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Detalles Bibliográficos
Autores principales:	Prakash, Ohm, Führing, Jana, Post, John, Shepherd, Sharon M., Eadsforth, Thomas C., Gray, David, Fedorov, Roman, Routier, Françoise H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429087/ https://www.ncbi.nlm.nih.gov/pubmed/30871023 http://dx.doi.org/10.3390/molecules24050996

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