Antiproliferative and Cytotoxic Activity of Xanthohumol and Its Non-Estrogenic Derivatives in Colon and Hepatocellular Carcinoma Cell Lines

Xanthohumol (XN), a prenylated flavonoid found in hops, inhibits growth in a variety of cancer cell lines; however, its use raises concerns as gut microbiota and the host’s hepatic cytochrome P450 enzymes metabolize it into the most potent phytoestrogen known, 8-prenylnaringenin (8-PN). The XN deriv...

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Detalles Bibliográficos
Autores principales: Logan, Isabelle E., Miranda, Cristobal L., Lowry, Malcolm B., Maier, Claudia S., Stevens, Jan F., Gombart, Adrian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429097/
https://www.ncbi.nlm.nih.gov/pubmed/30857300
http://dx.doi.org/10.3390/ijms20051203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429097/
https://www.ncbi.nlm.nih.gov/pubmed/30857300
http://dx.doi.org/10.3390/ijms20051203

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