Cargando…
Integrin β1-Mediated Cell–Cell Adhesion Augments Metformin-Induced Anoikis
Cell–cell adhesion plays an important role in regulation of cell proliferation, migration, survival, and drug sensitivity. Metformin, a first line drug for type 2 diabetes, has been shown to possess anti-cancer activities. However, whether cell–cell adhesion affects metformin anti-cancer activity is...
Autores principales: | An, Tingting, Zhang, Zhiming, Li, Yuhuang, Yi, Jianqiao, Zhang, Wenhua, Chen, Deshi, Ao, Juan, Xiao, Zhi-Xiong, Yi, Yong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429125/ https://www.ncbi.nlm.nih.gov/pubmed/30866414 http://dx.doi.org/10.3390/ijms20051161 |
Ejemplares similares
-
Role of p53 Family Proteins in Metformin Anti-Cancer Activities
por: Yi, Yong, et al.
Publicado: (2019) -
Integrin inhibition promotes atypical anoikis in glioma cells
por: Silginer, M, et al.
Publicado: (2014) -
Apigenin Attenuates Melanoma Cell Migration by Inducing Anoikis through Integrin and Focal Adhesion Kinase Inhibition
por: Hasnat, Md. Abul, et al.
Publicado: (2015) -
A small-molecule RGD-integrin antagonist inhibits cell adhesion, cell migration and induces anoikis in glioblastoma cells
por: RUSSO, MARIKA A., et al.
Publicado: (2012) -
FER kinase promotes breast cancer metastasis by regulating α(6)- and β(1)-integrin-dependent cell adhesion and anoikis resistance
por: Ivanova, I A, et al.
Publicado: (2013)