Compromised Chondrocyte Differentiation Capacity in TERC Knockout Mouse Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer

Mammalian telomere lengths are primarily regulated by telomerase, consisting of a reverse transcriptase protein (TERT) and an RNA subunit (TERC). We previously reported the generation of mouse Terc(+/−) and Terc(−/−) embryonic stem cells (ntESCs) by somatic cell nuclear transfer. In the present work...

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Detalles Bibliográficos
Autores principales: Chang, Wei-Fang, Wu, Yun-Hsin, Xu, Jie, Sung, Li-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429130/
https://www.ncbi.nlm.nih.gov/pubmed/30870992
http://dx.doi.org/10.3390/ijms20051236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429130/
https://www.ncbi.nlm.nih.gov/pubmed/30870992
http://dx.doi.org/10.3390/ijms20051236

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