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The Contribution of Genetic Factors to Cognitive Impairment and Dementia: Apolipoprotein E Gene, Gene Interactions, and Polygenic Risk

Alzheimer’s disease (AD) is a progressive neurodegenerative disease. Although it has been studied for years, the pathogenesis of AD is still controversial. Genetic factors may play an important role in pathogenesis, with the apolipoprotein E (APOE) gene among the greatest risk factors for AD. In thi...

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Detalles Bibliográficos
Autores principales:	Fan, Jialing, Tao, Wuhai, Li, Xin, Li, He, Zhang, Junying, Wei, Dongfeng, Chen, Yaojing, Zhang, Zhanjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429136/ https://www.ncbi.nlm.nih.gov/pubmed/30866553 http://dx.doi.org/10.3390/ijms20051177

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