Antrodin C, an NADPH Dependent Metabolism, Encourages Crosstalk between Autophagy and Apoptosis in Lung Carcinoma Cells by Use of an AMPK Inhibition-Independent Blockade of the Akt/mTOR Pathway

The current study aims to explore the possible anti-lung carcinoma activity of ADC as well as the underlying mechanisms by which ADC exerts its actions in NSCLC. Findings showed that ADC potently inhibited the viability of SPCA-1, induced apoptosis triggered by ROS, and arrested the cell cycle at th...

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Detalles Bibliográficos
Autores principales: Yang, Hairui, Bai, Xu, Zhang, Henan, Zhang, Jingsong, Wu, Yingying, Tang, Chuanhong, Liu, Yanfang, Yang, Yan, Liu, Zhendong, Jia, Wei, Wang, Wenhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429145/
https://www.ncbi.nlm.nih.gov/pubmed/30870998
http://dx.doi.org/10.3390/molecules24050993

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