Evolution and Biological Evaluation of Matrinic Derivatives with Amantadine Fragments As New Anti-Influenza Virus Agents

A series of novel tricyclic matrinic derivatives with 11-adamantyl substitution were designed, synthesized, and evaluated for their activities against Influenza A H3N2 virus, based on the privileged structure strategy. Structure-activity relationship (SAR) analysis indicated that the introduction of...

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Detalles Bibliográficos
Autores principales: Niu, Tianyu, Zhao, Xiaoqiang, Jiang, Jing, Yan, Haiyan, Li, Yinghong, Tang, Sheng, Li, Yuhuan, Song, Danqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429159/
https://www.ncbi.nlm.nih.gov/pubmed/30845734
http://dx.doi.org/10.3390/molecules24050921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429159/
https://www.ncbi.nlm.nih.gov/pubmed/30845734
http://dx.doi.org/10.3390/molecules24050921

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