Cell Metabolism Control Through O-GlcNAcylation of STAT5: A Full or Empty Fuel Tank Makes a Big Difference for Cancer Cell Growth and Survival

O-GlcNAcylation is a post-translational modification that influences tyrosine phosphorylation in healthy and malignant cells. O-GlcNAc is a product of the hexosamine biosynthetic pathway, a side pathway of glucose metabolism. It is essential for cell survival and proper gene regulation, mirroring th...

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Detalles Bibliográficos
Autores principales: Rauth, Manuel, Freund, Patricia, Orlova, Anna, Grünert, Stefan, Tasic, Nikola, Han, Xiaonan, Ruan, Hai-Bin, Neubauer, Heidi A., Moriggl, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429193/
https://www.ncbi.nlm.nih.gov/pubmed/30818760
http://dx.doi.org/10.3390/ijms20051028

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