Cargando…

Multi-Spheres Adsorptive Microextraction (MSAμE)—Application of a Novel Analytical Approach for Monitoring Chemical Anthropogenic Markers in Environmental Water Matrices

Multi-spheres adsorptive microextraction using powdered activated carbons (ACs) was studied as a novel enrichment approach, followed by liquid desorption and high-performance liquid chromatography with diode array detection (MSAµE(AC)-LD/HPLC-DAD) to monitor caffeine (CAF) and acetaminophen (ACF) tr...

Descripción completa

Detalles Bibliográficos
Autores principales: Silva, Ana R. M., Neng, Nuno R., Nogueira, José M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429196/
https://www.ncbi.nlm.nih.gov/pubmed/30866456
http://dx.doi.org/10.3390/molecules24050931
_version_ 1783405541727404032
author Silva, Ana R. M.
Neng, Nuno R.
Nogueira, José M. F.
author_facet Silva, Ana R. M.
Neng, Nuno R.
Nogueira, José M. F.
author_sort Silva, Ana R. M.
collection PubMed
description Multi-spheres adsorptive microextraction using powdered activated carbons (ACs) was studied as a novel enrichment approach, followed by liquid desorption and high-performance liquid chromatography with diode array detection (MSAµE(AC)-LD/HPLC-DAD) to monitor caffeine (CAF) and acetaminophen (ACF) traces in environmental matrices. In this study, commercial activated carbons (N, N(OX), and R) were tested, with the latter showing a much better performance for the analysis of both anthropogenic drugs. The main parameters affecting the efficiency of the proposed methodology are fully discussed using commercial AC(R). Textural and surface chemistry properties of the ACs sample were correlated with the analytical results. Assays performed on 30 mL of water samples spiked at 10 µg L(−1) under optimized experimental conditions, yielding recoveries of 75.3% for ACF and 82.6% for CAF. The methodology also showed excellent linear dynamic ranges for both drugs with determination coefficients higher than 0.9976, limits of detection and quantification of 0.8–1.2 µg L(−1) and 2.8–4.0 µg L(−1), respectively, and suitable precision (RSD < 13.8%). By using the standard addition method, the application of the present method to environmental matrices, including superficial, sea, and wastewater samples, allowed very good performance at the trace level. The proposed methodology proved to be a feasible alternative for polar compound analysis, showing to be easy to implement, reliable, and sensitive, with the possibility to reuse and store the analytical devices loaded with the target compounds for later analysis.
format Online
Article
Text
id pubmed-6429196
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-64291962019-04-15 Multi-Spheres Adsorptive Microextraction (MSAμE)—Application of a Novel Analytical Approach for Monitoring Chemical Anthropogenic Markers in Environmental Water Matrices Silva, Ana R. M. Neng, Nuno R. Nogueira, José M. F. Molecules Article Multi-spheres adsorptive microextraction using powdered activated carbons (ACs) was studied as a novel enrichment approach, followed by liquid desorption and high-performance liquid chromatography with diode array detection (MSAµE(AC)-LD/HPLC-DAD) to monitor caffeine (CAF) and acetaminophen (ACF) traces in environmental matrices. In this study, commercial activated carbons (N, N(OX), and R) were tested, with the latter showing a much better performance for the analysis of both anthropogenic drugs. The main parameters affecting the efficiency of the proposed methodology are fully discussed using commercial AC(R). Textural and surface chemistry properties of the ACs sample were correlated with the analytical results. Assays performed on 30 mL of water samples spiked at 10 µg L(−1) under optimized experimental conditions, yielding recoveries of 75.3% for ACF and 82.6% for CAF. The methodology also showed excellent linear dynamic ranges for both drugs with determination coefficients higher than 0.9976, limits of detection and quantification of 0.8–1.2 µg L(−1) and 2.8–4.0 µg L(−1), respectively, and suitable precision (RSD < 13.8%). By using the standard addition method, the application of the present method to environmental matrices, including superficial, sea, and wastewater samples, allowed very good performance at the trace level. The proposed methodology proved to be a feasible alternative for polar compound analysis, showing to be easy to implement, reliable, and sensitive, with the possibility to reuse and store the analytical devices loaded with the target compounds for later analysis. MDPI 2019-03-07 /pmc/articles/PMC6429196/ /pubmed/30866456 http://dx.doi.org/10.3390/molecules24050931 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Silva, Ana R. M.
Neng, Nuno R.
Nogueira, José M. F.
Multi-Spheres Adsorptive Microextraction (MSAμE)—Application of a Novel Analytical Approach for Monitoring Chemical Anthropogenic Markers in Environmental Water Matrices
title Multi-Spheres Adsorptive Microextraction (MSAμE)—Application of a Novel Analytical Approach for Monitoring Chemical Anthropogenic Markers in Environmental Water Matrices
title_full Multi-Spheres Adsorptive Microextraction (MSAμE)—Application of a Novel Analytical Approach for Monitoring Chemical Anthropogenic Markers in Environmental Water Matrices
title_fullStr Multi-Spheres Adsorptive Microextraction (MSAμE)—Application of a Novel Analytical Approach for Monitoring Chemical Anthropogenic Markers in Environmental Water Matrices
title_full_unstemmed Multi-Spheres Adsorptive Microextraction (MSAμE)—Application of a Novel Analytical Approach for Monitoring Chemical Anthropogenic Markers in Environmental Water Matrices
title_short Multi-Spheres Adsorptive Microextraction (MSAμE)—Application of a Novel Analytical Approach for Monitoring Chemical Anthropogenic Markers in Environmental Water Matrices
title_sort multi-spheres adsorptive microextraction (msaμe)—application of a novel analytical approach for monitoring chemical anthropogenic markers in environmental water matrices
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429196/
https://www.ncbi.nlm.nih.gov/pubmed/30866456
http://dx.doi.org/10.3390/molecules24050931
work_keys_str_mv AT silvaanarm multispheresadsorptivemicroextractionmsameapplicationofanovelanalyticalapproachformonitoringchemicalanthropogenicmarkersinenvironmentalwatermatrices
AT nengnunor multispheresadsorptivemicroextractionmsameapplicationofanovelanalyticalapproachformonitoringchemicalanthropogenicmarkersinenvironmentalwatermatrices
AT nogueirajosemf multispheresadsorptivemicroextractionmsameapplicationofanovelanalyticalapproachformonitoringchemicalanthropogenicmarkersinenvironmentalwatermatrices