Regulatory Effect of DNA Topoisomerase I on T3SS Activity, Antibiotic Susceptibility and Quorum- Sensing-Independent Pyocyanin Synthesis in Pseudomonas aeruginosa

Topoisomerases are required for alleviating supercoiling of DNA during transcription and replication. Recent evidence suggests that supercoiling of bacterial DNA can affect bacterial pathogenicity. To understand the potential regulatory role of a topoisomerase I (TopA) in Pseudomonas aeruginosa, we...

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Detalles Bibliográficos
Autores principales: Yan, Rong, Hu, Shikun, Ma, Ning, Song, Peiqing, Liang, Qingqing, Zhang, Huiqun, Li, Yanqi, Shen, Lixin, Duan, Kangmin, Chen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429228/
https://www.ncbi.nlm.nih.gov/pubmed/30841529
http://dx.doi.org/10.3390/ijms20051116

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