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Role of GirK Channels in Long-Term Potentiation of Synaptic Inhibition in an In Vivo Mouse Model of Early Amyloid-β Pathology

Imbalances of excitatory/inhibitory synaptic transmission occur early in the pathogenesis of Alzheimer’s disease (AD), leading to hippocampal hyperexcitability and causing synaptic, network, and cognitive dysfunctions. G-protein-gated potassium (GirK) channels play a key role in the control of neuro...

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Detalles Bibliográficos
Autores principales: Sánchez-Rodríguez, Irene, Gruart, Agnès, Delgado-García, José María, Jiménez-Díaz, Lydia, Navarro-López, Juan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429279/
https://www.ncbi.nlm.nih.gov/pubmed/30866445
http://dx.doi.org/10.3390/ijms20051168

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