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An Economic, Modular, and Portable Skin Viscoelasticity Measurement Device for In Situ Longitudinal Studies

A indentation-based device to measure tissue mechanical property was designed and built using over-the-counter and 3D-printed parts. The device costs less than 100 USD and is capable of measuring samples of various geometry because of its modular design. The device is light-weight, thus portable, fo...

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Detalles Bibliográficos
Autores principales: Park, Seungman, Tao, Jiaxiang, Sun, Li, Fan, Chen-Ming, Chen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429284/
https://www.ncbi.nlm.nih.gov/pubmed/30841558
http://dx.doi.org/10.3390/molecules24050907
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author Park, Seungman
Tao, Jiaxiang
Sun, Li
Fan, Chen-Ming
Chen, Yun
author_facet Park, Seungman
Tao, Jiaxiang
Sun, Li
Fan, Chen-Ming
Chen, Yun
author_sort Park, Seungman
collection PubMed
description A indentation-based device to measure tissue mechanical property was designed and built using over-the-counter and 3D-printed parts. The device costs less than 100 USD and is capable of measuring samples of various geometry because of its modular design. The device is light-weight, thus portable, for measurements that can be performed at different sites. It was demonstrated that the measurement results obtained using our device are comparable to previous observations. The elastic shear modulus of the human skin was in the range of 2 kPa to 8 kPa, and skin tissues in old mice were stiffer than young mice. Mechanical properties of the skin tissues belonging to the same test subject varied depending on the location of the measurement. In conclusion, because our device is economic, modular, portable, and robust, it is suitable to serve as a standard measurement platform for studying tissue mechanics.
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spelling pubmed-64292842019-04-15 An Economic, Modular, and Portable Skin Viscoelasticity Measurement Device for In Situ Longitudinal Studies Park, Seungman Tao, Jiaxiang Sun, Li Fan, Chen-Ming Chen, Yun Molecules Article A indentation-based device to measure tissue mechanical property was designed and built using over-the-counter and 3D-printed parts. The device costs less than 100 USD and is capable of measuring samples of various geometry because of its modular design. The device is light-weight, thus portable, for measurements that can be performed at different sites. It was demonstrated that the measurement results obtained using our device are comparable to previous observations. The elastic shear modulus of the human skin was in the range of 2 kPa to 8 kPa, and skin tissues in old mice were stiffer than young mice. Mechanical properties of the skin tissues belonging to the same test subject varied depending on the location of the measurement. In conclusion, because our device is economic, modular, portable, and robust, it is suitable to serve as a standard measurement platform for studying tissue mechanics. MDPI 2019-03-05 /pmc/articles/PMC6429284/ /pubmed/30841558 http://dx.doi.org/10.3390/molecules24050907 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Park, Seungman
Tao, Jiaxiang
Sun, Li
Fan, Chen-Ming
Chen, Yun
An Economic, Modular, and Portable Skin Viscoelasticity Measurement Device for In Situ Longitudinal Studies
title An Economic, Modular, and Portable Skin Viscoelasticity Measurement Device for In Situ Longitudinal Studies
title_full An Economic, Modular, and Portable Skin Viscoelasticity Measurement Device for In Situ Longitudinal Studies
title_fullStr An Economic, Modular, and Portable Skin Viscoelasticity Measurement Device for In Situ Longitudinal Studies
title_full_unstemmed An Economic, Modular, and Portable Skin Viscoelasticity Measurement Device for In Situ Longitudinal Studies
title_short An Economic, Modular, and Portable Skin Viscoelasticity Measurement Device for In Situ Longitudinal Studies
title_sort economic, modular, and portable skin viscoelasticity measurement device for in situ longitudinal studies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429284/
https://www.ncbi.nlm.nih.gov/pubmed/30841558
http://dx.doi.org/10.3390/molecules24050907
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