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Population Substructure Has Implications in Validating Next-Generation Cancer Genomics Studies with TCGA

In the era of large genetic and genomic datasets, it has become crucially important to validate results of individual studies using data from publicly available sources, such as The Cancer Genome Atlas (TCGA). However, how generalizable are results from either an independent or a large public datase...

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Detalles Bibliográficos
Autores principales: Miller, Marina D., Devor, Eric J., Salinas, Erin A., Newtson, Andreea M., Goodheart, Michael J., Leslie, Kimberly K., Gonzalez-Bosquet, Jesus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429328/
https://www.ncbi.nlm.nih.gov/pubmed/30857229
http://dx.doi.org/10.3390/ijms20051192