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Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks
Aging and various age-related diseases are associated with reductions in melatonin secretion, proinflammatory changes in the immune system, a deteriorating circadian system, and reductions in sirtuin-1 (SIRT1) activity. In non-tumor cells, several effects of melatonin are abolished by inhibiting SIR...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429360/ https://www.ncbi.nlm.nih.gov/pubmed/30862067 http://dx.doi.org/10.3390/ijms20051223 |