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Strong Inhibition of Cholera Toxin B Subunit by Affordable, Polymer-Based Multivalent Inhibitors
[Image: see text] Cholera is a potentially fatal bacterial infection that affects a large number of people in developing countries. It is caused by the cholera toxin (CT), an AB(5) toxin secreted by Vibrio cholera. The toxin comprises a toxic A-subunit and a pentameric B-subunit that bind to the int...
Autores principales: | Haksar, Diksha, de Poel, Eyleen, van Ufford, Linda Quarles, Bhatia, Sumati, Haag, Rainer, Beekman, Jeffrey, Pieters, Roland J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429436/ https://www.ncbi.nlm.nih.gov/pubmed/30629410 http://dx.doi.org/10.1021/acs.bioconjchem.8b00902 |
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