Bacillus anthracis Edema Toxin Inhibits Efferocytosis in Human Macrophages and Alters Efferocytic Receptor Signaling

The Bacillus anthracis Edema Toxin (ET), composed of a Protective Antigen (PA) and the Edema Factor (EF), is a cellular adenylate cyclase that alters host responses by elevating cyclic adenosine monophosphate (cAMP) to supraphysiologic levels. However, the role of ET in systemic anthrax is unclear....

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Detalles Bibliográficos
Autores principales: Pan, Zijian, Dumas, Eric K., Lawrence, Christina, Pate, Lance, Longobardi, Sherri, Wang, Xiaodong, James, Judith A., Kovats, Susan, Farris, A. Darise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429438/
https://www.ncbi.nlm.nih.gov/pubmed/30866434
http://dx.doi.org/10.3390/ijms20051167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429438/
https://www.ncbi.nlm.nih.gov/pubmed/30866434
http://dx.doi.org/10.3390/ijms20051167

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