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Genotoxic Effects of Tributyltin and Triphenyltin Isothiocyanates, Cognate RXR Ligands: Comparison in Human Breast Carcinoma MCF 7 and MDA-MB-231 Cells

The cytotoxicity of two recently synthesized triorganotin isothiocyanate derivatives, nuclear retinoid X receptor ligands, was tested and compared in estrogen-receptor-positive MCF 7 and -negative MDA-MB-231 human breast carcinoma cell lines. A 48 h MTT assay indicated that tributyltin isothiocyanat...

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Detalles Bibliográficos
Autores principales: Hunakova, Luba, Horvathova, Eva, Majerova, Karolina, Bobal, Pavel, Otevrel, Jan, Brtko, Julius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429456/
https://www.ncbi.nlm.nih.gov/pubmed/30857277
http://dx.doi.org/10.3390/ijms20051198

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