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APE-Gen: A Fast Method for Generating Ensembles of Bound Peptide-MHC Conformations

The Class I Major Histocompatibility Complex (MHC) is a central protein in immunology as it binds to intracellular peptides and displays them at the cell surface for recognition by T-cells. The structural analysis of bound peptide-MHC complexes (pMHCs) holds the promise of interpretable and general...

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Detalles Bibliográficos
Autores principales:	Abella, Jayvee R., Antunes, Dinler A., Clementi, Cecilia, Kavraki, Lydia E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429480/ https://www.ncbi.nlm.nih.gov/pubmed/30832312 http://dx.doi.org/10.3390/molecules24050881

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