Cargando…

Synthesis and AChE-Inhibitory Activity of New Benzimidazole Derivatives

Alzheimer’s disease (AD), one of the main causes of aged dementia, is a progressive and degenerative neurological disorder characterized by loss of cognition and memory. Although the symptomatic treatment of AD, particularly acetylcholinesterase inhibitors (AChEIs) based on the ‘cholinergic hypothes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Acar Cevik, Ulviye, Saglik, Begüm Nurpelin, Levent, Serkan, Osmaniye, Derya, Kaya Cavuşoglu, Betul, Ozkay, Yusuf, Kaplancikli, Zafer Asim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429502/ https://www.ncbi.nlm.nih.gov/pubmed/30823470 http://dx.doi.org/10.3390/molecules24050861

Ejemplares similares

Synthesis and AChE Inhibitory Activity of Novel Thiazolylhydrazone Derivatives
por: Osmaniye, Derya, et al.
Publicado: (2019)

Synthesis and Anticandidal Activity Evaluation of New Benzimidazole-Thiazole Derivatives
por: Kaplancıklı, Zafer Asım, et al.
Publicado: (2017)

Synthesis, Docking Studies and Biological Activity of New Benzimidazole- Triazolothiadiazine Derivatives as Aromatase Inhibitor
por: Acar Çevik, Ulviye, et al.
Publicado: (2020)

Design, Synthesis, and Structure–Activity Relationships of Thiazole Analogs as Anticholinesterase Agents for Alzheimer’s Disease
por: Sağlık, Begüm Nurpelin, et al.
Publicado: (2020)

Synthesis and Biological Evaluation of New Thiosemicarbazone Derivative Schiff Bases as Monoamine Oxidase Inhibitory Agents
por: Çavuşoğlu, Betül Kaya, et al.
Publicado: (2017)

Synthesis and Anticandidal Activity of New Imidazole-Chalcones
por: Osmaniye, Derya, et al.
Publicado: (2018)

Synthesis of Oxadiazole-Thiadiazole Hybrids and Their Anticandidal Activity
por: Levent, Serkan, et al.
Publicado: (2017)

Synthesis, anticancer evaluation and molecular docking studies of new benzimidazole- 1,3,4-oxadiazole derivatives as human topoisomerase types I poison
por: Acar Çevik, Ulviye, et al.
Publicado: (2020)

Design and Synthesis of New Benzothiazole Compounds as Selective hMAO-B Inhibitors
por: Ilgın, Sinem, et al.
Publicado: (2017)

Synthesis and Antifungal Potential of Some Novel Benzimidazole-1,3,4-Oxadiazole Compounds
por: Karaburun, Ahmet Çağrı, et al.
Publicado: (2019)

Design, Synthesis, In Vitro and In Silico Studies of New Thiazolylhydrazine-Piperazine Derivatives as Selective MAO-A Inhibitors
por: Sağlık, Begüm Nurpelin, et al.
Publicado: (2020)

Synthesis, in vitro enzyme activity and molecular docking studies of new benzylamine-sulfonamide derivatives as selective MAO-B inhibitors
por: Sağlık, Begüm Nurpelin, et al.
Publicado: (2020)

Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Potent Antifungal Agents
por: Karaburun, Ahmet Çağrı, et al.
Publicado: (2018)

Design, synthesis, and evaluation of novel 2-phenylpropionic acid derivatives as dual COX inhibitory-antibacterial agents
por: Karaca Gençer, Hülya, et al.
Publicado: (2017)

Synthesis and Anticancer Activities of Pyrazole–Thiadiazole-Based EGFR Inhibitors
por: Kurban, Berkant, et al.
Publicado: (2023)

Synthesis of New Hydrazone Derivatives for MAO Enzymes Inhibitory Activity
por: Can, Nafiz Öncü, et al.
Publicado: (2017)

Novel Thiosemicarbazone Derivatives: In Vitro and In Silico Evaluation as Potential MAO-B Inhibitors
por: Osmaniye, Derya, et al.
Publicado: (2021)

Design, Synthesis, and Evaluation of Novel 2H-Benzo[b][1,4]thiazin-3(4H)-one Derivatives as New Acetylcholinesterase Inhibitors
por: Haji Ali, Sazan, et al.
Publicado: (2022)

Synthesis of novel benzothiazole derivatives and investigation of their enzyme inhibitory effects against Alzheimer's disease
por: Karaca, Şevval, et al.
Publicado: (2022)

Design, Synthesis, and In Vitro and In Silico Approaches of Novel Indanone Derivatives as Multifunctional Anti-Alzheimer Agents
por: Sağlık, Begüm Nurpelin, et al.
Publicado: (2022)

Synthesis, Antifungal Activities, Molecular Docking and Molecular Dynamic Studies of Novel Quinoxaline-Triazole Compounds
por: Osmaniye, Derya, et al.
Publicado: (2023)

Novel 1-(2-pyrimidin-2-yl)piperazine derivatives as selective monoamine oxidase (MAO)-A inhibitors
por: Kaya, Betül, et al.
Publicado: (2017)

Design, Synthesis, and Biological Evaluation Studies of Novel Naphthalene-Chalcone Hybrids As Antimicrobial, Anticandidal, Anticancer, and VEGFR-2 Inhibitors
por: Osmaniye, Derya, et al.
Publicado: (2023)

New Benzimidazole-1,2,4-Triazole Hybrid Compounds: Synthesis, Anticandidal Activity and Cytotoxicity Evaluation
por: Karaca Gençer, Hülya, et al.
Publicado: (2017)

Design, Synthesis, and Molecular Modeling Studies of a Novel Benzimidazole as an Aromatase Inhibitor
por: Çevik, Ulviye Acar, et al.
Publicado: (2022)

Synthesis of New Fluoro-Benzimidazole Derivatives as an Approach towards the Discovery of Novel Intestinal Antiseptic Drug Candidates
por: Çevik, Ulviye Acar, et al.
Publicado: (2017)

Synthesis and Biological Evaluation of New Cholinesterase Inhibitors for Alzheimer’s Disease
por: Hussein, Weiam, et al.
Publicado: (2018)

Pharmacological and Toxicological Screening of Novel Benzimidazole-Morpholine Derivatives as Dual-Acting Inhibitors
por: Can, Nafiz Öncü, et al.
Publicado: (2017)

Synthesis of New Benzothiazole Acylhydrazones as Anticancer Agents
por: Osmaniye, Derya, et al.
Publicado: (2018)

Synthesis and Molecular Docking of New N-Acyl Hydrazones-Benzimidazole as hCA I and II Inhibitors
por: Küçükoğlu, Kaan, et al.
Publicado: (2023)

Synthesis of Benzimidazole-1,2,4-triazole Derivatives as Potential Antifungal Agents Targeting 14α-Demethylase
por: Güzel, Emir, et al.
Publicado: (2023)

Synthesis, Molecular Docking, Dynamics, Quantum-Chemical Computation, and Antimicrobial Activity Studies of Some New Benzimidazole–Thiadiazole Hybrids
por: Celik, Ismail, et al.
Publicado: (2022)

Synthesis of Novel Benzazole Derivatives and Evaluation of Their Antidepressant-Like Activities with Possible Underlying Mechanisms
por: Tokgöz, Gamze, et al.
Publicado: (2018)

Synthesis and Antidepressant Activity Profile of Some Novel Benzothiazole Derivatives
por: Demir Özkay, Ümide, et al.
Publicado: (2017)

Investigation of Novel Quinoline–Thiazole Derivatives as Antimicrobial Agents: In Vitro and In Silico Approaches
por: Evren, Asaf Evrim, et al.
Publicado: (2022)

Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Antinociceptive Agents
por: Altıntop, Mehlika Dilek, et al.
Publicado: (2016)

The 4-(dimethylaminoalkyl)piperazine inhibitors of α-glucosidase: allosteric enzyme inhibition and identification of interacting chemical groups
por: GHANI, Usman, et al.
Publicado: (2022)

Synthesis of Some Oxadiazole Derivatives as New Anticandidal Agents
por: Kaplancikli, Zafer Asim
Publicado: (2011)

Synthesis of Some Novel Thiadiazole Derivative Compounds and Screening Their Antidepressant-Like Activities
por: Can, Nafiz Öncü, et al.
Publicado: (2018)

Synthesis and Evaluation of New 1,5-Diaryl-3-[4-(methyl-sulfonyl)phenyl]-4,5-dihydro-1H-pyrazole Derivatives as Potential Antidepressant Agents
por: Özdemir, Ahmet, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_eofha66mhpnp105ppljlnsm4dp