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Extracellular Spermine Activates DNA Methyltransferase 3A and 3B

We first demonstrated that long-term increased polyamine (spermine, spermidine, putrescine) intake elevated blood spermine levels in mice and humans, and lifelong consumption of polyamine-rich chow inhibited aging-associated increase in aberrant DNA methylation, inhibited aging-associated pathologic...

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Detalles Bibliográficos
Autores principales:	Fukui, Taro, Soda, Kuniyasu, Takao, Koichi, Rikiyama, Toshiki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429523/ https://www.ncbi.nlm.nih.gov/pubmed/30871110 http://dx.doi.org/10.3390/ijms20051254

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