Cargando…

Synthesis of (18)F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [(18)F]fluoride

Herein, we report the radiosynthesis of (18)F-difluoromethylarenes via the assembly of three components, a boron reagent, ethyl bromofluoroacetate, and cyclotron-produced non-carrier added [(18)F]fluoride. The two key steps are a copper-catalysed cross-coupling reaction, and a Mn-mediated (18)F-fluo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sap, Jeroen B. I., Wilson, Thomas C., Kee, Choon Wee, Straathof, Natan J. W., Ende, Christopher W. am, Mukherjee, Paramita, Zhang, Lei, Genicot, Christophe, Gouverneur, Véronique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429591/ https://www.ncbi.nlm.nih.gov/pubmed/30996907 http://dx.doi.org/10.1039/c8sc05096a

Ejemplares similares

Multi-patient dose synthesis of [(18)F]Flumazenil via a copper-mediated (18)F-fluorination
por: Gendron, Thibault, et al.
Publicado: (2022)

[(18)F]Tosyl fluoride as a versatile [(18)F]fluoride source for the preparation of (18)F-labeled radiopharmaceuticals
por: Zhou, Dong, et al.
Publicado: (2023)

Pd-Catalyzed α-Arylation of α,α-Difluoroketones with Aryl Bromides and Chlorides. A Route to Difluoromethylarenes
por: Ge, Shaozhong, et al.
Publicado: (2014)

Fast and efficient copper-mediated (18)F-fluorination of arylstannanes, aryl boronic acids, and aryl boronic esters without azeotropic drying
por: Lahdenpohja, Salla Orvokki, et al.
Publicado: (2019)

Organophotoredox Hydrodefluorination of Trifluoromethylarenes with Translational Applicability to Drug Discovery
por: Sap, Jeroen B. I., et al.
Publicado: (2020)

Closing the gap between (19)F and (18)F chemistry
por: Ajenjo, Javier, et al.
Publicado: (2021)

(18)F-Sodium Fluoride ((18)F-NaF) for Imaging Microcalcification Activity in the Cardiovascular System
por: Tzolos, Evangelos, et al.
Publicado: (2020)

Correction to: Closing the gap between (19)F and (18)F chemistry
por: Ajenjo, Javier, et al.
Publicado: (2022)

Synthesis of [(18)F]Arenes via the Copper-Mediated [(18)F]Fluorination of Boronic Acids
por: Mossine, Andrew V., et al.
Publicado: (2015)

(18)F-Trifluoromethanesulfinate Enables Direct C–H (18)F-Trifluoromethylation of Native Aromatic Residues in Peptides
por: Kee, Choon Wee, et al.
Publicado: (2020)

Asymmetric (18)F-fluorination for applications in positron emission tomography
por: Buckingham, Faye, et al.
Publicado: (2016)

Radiofluorination using aluminum-fluoride (Al(18)F)
por: McBride, William J, et al.
Publicado: (2013)

(18)F-fluoride PET/CT in clinical practice
por: Ramos, Celso Darío
Publicado: (2015)

Atherosclerosis Imaging with (18)F-Sodium Fluoride PET
por: Høilund-Carlsen, Poul F., et al.
Publicado: (2020)

Calcified peritoneal metastasis identified on 18F-fluoride positron emission tomography/computed tomography: Importance of extraosseous uptake of F-18 fluoride
por: Verma, Priyanka, et al.
Publicado: (2016)

Automated Radiosynthesis of cis- and trans-4-[(18)F]Fluoro-l-proline Using [(18)F]Fluoride
por: Morgan, Timaeus E. F., et al.
Publicado: (2021)

Analysis of (18)F-Fluorodeoxyglucose and (18)F-Fluoride Positron Emission Tomography in Korean Stroke Patients with Carotid Atherosclerosis
por: Kim, Jeong-Min, et al.
Publicado: (2019)

An Update on [(18)F]Fluoride PET Imaging for Atherosclerotic Disease
por: Lee, Reeree, et al.
Publicado: (2020)

Molecular Coronary Plaque Imaging Using (18)F-Fluoride
por: Moss, Alastair J., et al.
Publicado: (2019)

Fully automated peptide radiolabeling from [(18)F]fluoride
por: Davis, Ryan A., et al.
Publicado: (2019)

A Transmetalation Reaction Enables the Synthesis of [(18)F]5-Fluorouracil from [(18)F]Fluoride for Human PET Imaging
por: Hoover, Andrew J., et al.
Publicado: (2016)

On site production of [(18)F]PSMA-1007 using different [(18)F]fluoride activities: practical, technical and economical impact
por: Maisto, Costantina, et al.
Publicado: (2021)

Is Response Assessment of Breast Cancer Bone Metastases Better with Measurement of (18)F-Fluoride Metabolic Flux Than with Measurement of (18)F-Fluoride PET/CT SUV?
por: Azad, Gurdip K., et al.
Publicado: (2019)

Synthesis of Fluorinated Alkyl Aryl Ethers by Palladium-Catalyzed C–O Cross-Coupling
por: Szpera, Robert, et al.
Publicado: (2020)

Copper-Catalyzed [(18)F]Fluorination of (Mesityl)(aryl)iodonium Salts
por: Ichiishi, Naoko, et al.
Publicado: (2014)

Recent Development of Radiofluorination of Boron Agents for Boron Neutron Capture Therapy of Tumor: Creation of (18)F-Labeled C-F and B-F Linkages
por: Deng, Jin-Pei, et al.
Publicado: (2023)

(18)F-meta-fluorobenzylguanidine ((18)F-mFBG) to monitor changes in norepinephrine transporter expression in response to therapeutic intervention in neuroblastoma models
por: Turnock, Stephen, et al.
Publicado: (2020)

Coronary (18)F-Fluoride Uptake and Progression of Coronary Artery Calcification
por: Doris, Mhairi K., et al.
Publicado: (2020)

Advances in Quantitative Analysis of (18)F-Sodium Fluoride Coronary Imaging
por: Kwiecinski, Jacek, et al.
Publicado: (2021)

[(18)F] Sodium Fluoride PET Kinetic Parameters in Bone Imaging
por: Puri, Tanuj, et al.
Publicado: (2021)

Quantifying sodium [(18)F]fluoride uptake in abdominal aortic aneurysms
por: Debono, Samuel, et al.
Publicado: (2022)

Assessment of metabolic patterns and new antitumoral treatment in osteosarcoma xenograft models by [(18)F]FDG and sodium [(18)F]fluoride PET
por: Collantes, María, et al.
Publicado: (2018)

Enhanced Aqueous Suzuki–Miyaura Coupling Allows Site-Specific Polypeptide (18)F-Labeling
por: Gao, Zhanghua, et al.
Publicado: (2013)

(18)F-Sodium Fluoride (NaF) Uptake in Calcified Bladder Carcinoma: Double Density Sign
por: Usmani, Sharjeel, et al.
Publicado: (2021)

Dataset on the synthesis and characterization of boron fenbufen and its F-18 labeled homolog
por: Yeh, Chun-Nan, et al.
Publicado: (2017)

Assessment of a (18)F-Phenylboronic Acid Radiotracer for Imaging Boron in Maize
por: Housh, Alexandra B., et al.
Publicado: (2020)

PET imaging of HER2 expression with an (18)F-fluoride labeled aptamer
por: Kim, Hyun Jeong, et al.
Publicado: (2019)

Occult Hip Prosthetic Loosening Diagnosed by [18F] Fluoride-PET/CT
por: Ullmark, Gösta
Publicado: (2020)

Atherosclerosis imaging with (18)F-sodium fluoride PET: state-of-the-art review
por: Høilund-Carlsen, Poul F., et al.
Publicado: (2019)

A kit-based aluminium-[(18)F]fluoride approach to radiolabelled microbubbles
por: Teh, Jin Hui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_re5t4pgrpagsi15rjo6hhuo51a