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Rh(III)-Catalyzed Annulation of Boc-Protected Benzamides with Diazo Compounds: Approach to Isocoumarins
A mild rhodium-catalyzed annulation of Boc-protected benzamides with diazo compounds via C−C/C−O bond formation has been explored. In the presence of [Cp*RhCl(2)](2), AgSbF(6) and Cs(2)CO(3), Boc-protected benzamides can be effectively annulated to yield isocoumarins in 0.5–2 h.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429621/ https://www.ncbi.nlm.nih.gov/pubmed/30866510 http://dx.doi.org/10.3390/molecules24050937 |
| _version_ | 1783405630067834880 |
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| author | Dong, Guangyu Li, Chunpu Liu, Hong |
| author_facet | Dong, Guangyu Li, Chunpu Liu, Hong |
| author_sort | Dong, Guangyu |
| collection | PubMed |
| description | A mild rhodium-catalyzed annulation of Boc-protected benzamides with diazo compounds via C−C/C−O bond formation has been explored. In the presence of [Cp*RhCl(2)](2), AgSbF(6) and Cs(2)CO(3), Boc-protected benzamides can be effectively annulated to yield isocoumarins in 0.5–2 h. |
| format | Online Article Text |
| id | pubmed-6429621 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-64296212019-04-15 Rh(III)-Catalyzed Annulation of Boc-Protected Benzamides with Diazo Compounds: Approach to Isocoumarins Dong, Guangyu Li, Chunpu Liu, Hong Molecules Article A mild rhodium-catalyzed annulation of Boc-protected benzamides with diazo compounds via C−C/C−O bond formation has been explored. In the presence of [Cp*RhCl(2)](2), AgSbF(6) and Cs(2)CO(3), Boc-protected benzamides can be effectively annulated to yield isocoumarins in 0.5–2 h. MDPI 2019-03-07 /pmc/articles/PMC6429621/ /pubmed/30866510 http://dx.doi.org/10.3390/molecules24050937 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Article Dong, Guangyu Li, Chunpu Liu, Hong Rh(III)-Catalyzed Annulation of Boc-Protected Benzamides with Diazo Compounds: Approach to Isocoumarins |
| title | Rh(III)-Catalyzed Annulation of Boc-Protected Benzamides with Diazo Compounds: Approach to Isocoumarins |
| title_full | Rh(III)-Catalyzed Annulation of Boc-Protected Benzamides with Diazo Compounds: Approach to Isocoumarins |
| title_fullStr | Rh(III)-Catalyzed Annulation of Boc-Protected Benzamides with Diazo Compounds: Approach to Isocoumarins |
| title_full_unstemmed | Rh(III)-Catalyzed Annulation of Boc-Protected Benzamides with Diazo Compounds: Approach to Isocoumarins |
| title_short | Rh(III)-Catalyzed Annulation of Boc-Protected Benzamides with Diazo Compounds: Approach to Isocoumarins |
| title_sort | rh(iii)-catalyzed annulation of boc-protected benzamides with diazo compounds: approach to isocoumarins |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429621/ https://www.ncbi.nlm.nih.gov/pubmed/30866510 http://dx.doi.org/10.3390/molecules24050937 |
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