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Lycopene improves the efficiency of anti-PD-1 therapy via activating IFN signaling of lung cancer cells

BACKGROUND: Monoclonal antibodies targeting programmed death-1 receptor (PD-1) and its ligand (PD-L1) have been developed to treat cancers including lung cancer. In this study, we aimed to investigate whether lycopene could promote the effect of anti-PD-1 treatment on lung cancer. METHODS: Tumor for...

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Detalles Bibliográficos
Autores principales: Jiang, Xiufeng, Wu, Hui, Zhao, Wei, Ding, Xiao, You, Qian, Zhu, Feng, Qian, Meifang, Yu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429703/
https://www.ncbi.nlm.nih.gov/pubmed/30948928
http://dx.doi.org/10.1186/s12935-019-0789-y