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Discovery of a natural small-molecule compound that suppresses tumor EMT, stemness and metastasis by inhibiting TGFβ/BMP signaling in triple-negative breast cancer

BACKGROUND: The transforming growth factor β (TGFβ) and bone morphogenetic protein (BMP) signaling pathways are both constitutively activated in triple-negative breast cancer (TNBC). We are interested in isolating the naturally-derived small-molecule inhibitor that could simultaneously targeting TGF...

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Detalles Bibliográficos
Autores principales:	Di, Lei, Liu, Li-Juan, Yan, Yong-Ming, Fu, Rong, Li, Yi, Xu, Ying, Cheng, Yong-Xian, Wu, Zhao-Qiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429712/ https://www.ncbi.nlm.nih.gov/pubmed/30898152 http://dx.doi.org/10.1186/s13046-019-1130-2

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