Trabectedin triggers direct and NK-mediated cytotoxicity in multiple myeloma

BACKGROUND: Genomic instability is a feature of multiple myeloma (MM), and impairment in DNA damaging response (DDR) has an established role in disease pathobiology. Indeed, a deregulation of DNA repair pathways may contribute to genomic instability, to the establishment of drug resistance to genoto...

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Detalles Bibliográficos
Autores principales: Cucè, Maria, Gallo Cantafio, Maria Eugenia, Siciliano, Maria Anna, Riillo, Caterina, Caracciolo, Daniele, Scionti, Francesca, Staropoli, Nicoletta, Zuccalà, Valeria, Maltese, Lorenza, Di Vito, Anna, Grillone, Katia, Barbieri, Vito, Arbitrio, Mariamena, Di Martino, Maria Teresa, Rossi, Marco, Amodio, Nicola, Tagliaferri, Pierosandro, Tassone, Pierfrancesco, Botta, Cirino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429746/
https://www.ncbi.nlm.nih.gov/pubmed/30898137
http://dx.doi.org/10.1186/s13045-019-0714-9

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