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Three different polymorphisms of the DPYD gene associated with severe toxicity following administration of 5-FU: a case report

BACKGROUND: Dihydropyrimidine dehydrogenase deficiency secondary to polymorphisms in the DPYD gene can lead to significant toxicity associated with the administration of fluoropyrimidine chemotherapy. CASE PRESENTATION: We report a case of a 59-year-old Lebanese woman with metastatic pancreatic canc...

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Detalles Bibliográficos
Autores principales:	Mukherji, Deborah, Massih, Sarah Abdel, Tfayli, Arafat, Kanso, Mariam, Faraj, Walid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429833/ https://www.ncbi.nlm.nih.gov/pubmed/30898145 http://dx.doi.org/10.1186/s13256-019-2013-z

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