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Association between access to social service resources and cardiometabolic risk factors: a machine learning and multilevel modeling analysis

OBJECTIVES: Interest in linking patients with unmet social needs to area-level resources, such as food pantries and employment centres in one’s ZIP code, is growing. However, whether the presence of these resources is associated with better health outcomes is unclear. We sought to determine if area-...

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Autores principales: Berkowitz, Seth A, Basu, Sanjay, Venkataramani, Atheendar, Reznor, Gally, Fleegler, Eric W, Atlas, Steven J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429845/
https://www.ncbi.nlm.nih.gov/pubmed/30862634
http://dx.doi.org/10.1136/bmjopen-2018-025281
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author Berkowitz, Seth A
Basu, Sanjay
Venkataramani, Atheendar
Reznor, Gally
Fleegler, Eric W
Atlas, Steven J
author_facet Berkowitz, Seth A
Basu, Sanjay
Venkataramani, Atheendar
Reznor, Gally
Fleegler, Eric W
Atlas, Steven J
author_sort Berkowitz, Seth A
collection PubMed
description OBJECTIVES: Interest in linking patients with unmet social needs to area-level resources, such as food pantries and employment centres in one’s ZIP code, is growing. However, whether the presence of these resources is associated with better health outcomes is unclear. We sought to determine if area-level resources, defined as organisations that assist individuals with meeting health-related social needs, are associated with lower levels of cardiometabolic risk factors. DESIGN: Cross-sectional. SETTING: Data were collected in a primary care network in eastern Massachusetts in 2015. PARTICIPANTS AND PRIMARY AND SECONDARY OUTCOME MEASURES: 123 355 participants were included. The primary outcome was body mass index (BMI). The secondary outcomes were systolic blood pressure (SBP), low-density lipoprotein (LDL) cholesterol and haemoglobin A1c (HbA1c). All participants were included in BMI analyses. Participants with hypertension were included in SBP analyses. Participants with an indication for cholesterol lowering were included in LDL analyses and participants with diabetes mellitus were included in HbA1c analyses. We used a random forest-based machine-learning algorithm to identify types of resources associated with study outcomes. We then tested the association of ZIP-level selected resource types (three for BMI, two each for SBP and HbA1c analyses and one for LDL analyses) with these outcomes, using multilevel models to account for individual-level, clinic-level and other area-level factors. RESULTS: Resources associated with lower BMI included more food resources (−0.08 kg/m(2) per additional resource, 95% CI −0.13 to −0.03 kg/m(2)), employment resources (−0.05 kg/m(2), 95% CI −0.11 to −0.002 kg/m(2)) and nutrition resources (−0.07 kg/m(2), 95% CI −0.13 to −0.01 kg/m(2)). No area resources were associated with differences in SBP, LDL or HbA1c. CONCLUSIONS: Access to specific local resources is associated with better BMI. Efforts to link patients to area resources, and to improve the resources landscape within communities, may help reduce BMI and improve population health.
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spelling pubmed-64298452019-04-05 Association between access to social service resources and cardiometabolic risk factors: a machine learning and multilevel modeling analysis Berkowitz, Seth A Basu, Sanjay Venkataramani, Atheendar Reznor, Gally Fleegler, Eric W Atlas, Steven J BMJ Open Epidemiology OBJECTIVES: Interest in linking patients with unmet social needs to area-level resources, such as food pantries and employment centres in one’s ZIP code, is growing. However, whether the presence of these resources is associated with better health outcomes is unclear. We sought to determine if area-level resources, defined as organisations that assist individuals with meeting health-related social needs, are associated with lower levels of cardiometabolic risk factors. DESIGN: Cross-sectional. SETTING: Data were collected in a primary care network in eastern Massachusetts in 2015. PARTICIPANTS AND PRIMARY AND SECONDARY OUTCOME MEASURES: 123 355 participants were included. The primary outcome was body mass index (BMI). The secondary outcomes were systolic blood pressure (SBP), low-density lipoprotein (LDL) cholesterol and haemoglobin A1c (HbA1c). All participants were included in BMI analyses. Participants with hypertension were included in SBP analyses. Participants with an indication for cholesterol lowering were included in LDL analyses and participants with diabetes mellitus were included in HbA1c analyses. We used a random forest-based machine-learning algorithm to identify types of resources associated with study outcomes. We then tested the association of ZIP-level selected resource types (three for BMI, two each for SBP and HbA1c analyses and one for LDL analyses) with these outcomes, using multilevel models to account for individual-level, clinic-level and other area-level factors. RESULTS: Resources associated with lower BMI included more food resources (−0.08 kg/m(2) per additional resource, 95% CI −0.13 to −0.03 kg/m(2)), employment resources (−0.05 kg/m(2), 95% CI −0.11 to −0.002 kg/m(2)) and nutrition resources (−0.07 kg/m(2), 95% CI −0.13 to −0.01 kg/m(2)). No area resources were associated with differences in SBP, LDL or HbA1c. CONCLUSIONS: Access to specific local resources is associated with better BMI. Efforts to link patients to area resources, and to improve the resources landscape within communities, may help reduce BMI and improve population health. BMJ Publishing Group 2019-03-12 /pmc/articles/PMC6429845/ /pubmed/30862634 http://dx.doi.org/10.1136/bmjopen-2018-025281 Text en © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Epidemiology
Berkowitz, Seth A
Basu, Sanjay
Venkataramani, Atheendar
Reznor, Gally
Fleegler, Eric W
Atlas, Steven J
Association between access to social service resources and cardiometabolic risk factors: a machine learning and multilevel modeling analysis
title Association between access to social service resources and cardiometabolic risk factors: a machine learning and multilevel modeling analysis
title_full Association between access to social service resources and cardiometabolic risk factors: a machine learning and multilevel modeling analysis
title_fullStr Association between access to social service resources and cardiometabolic risk factors: a machine learning and multilevel modeling analysis
title_full_unstemmed Association between access to social service resources and cardiometabolic risk factors: a machine learning and multilevel modeling analysis
title_short Association between access to social service resources and cardiometabolic risk factors: a machine learning and multilevel modeling analysis
title_sort association between access to social service resources and cardiometabolic risk factors: a machine learning and multilevel modeling analysis
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429845/
https://www.ncbi.nlm.nih.gov/pubmed/30862634
http://dx.doi.org/10.1136/bmjopen-2018-025281
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