Cargando…

Prevalence and characteristics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in Poland: a cross-sectional study

OBJECTIVES: The aim of this study was to estimate the prevalence of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and describe illness characteristics in a community population in Poland. Design: cross-sectional study. SETTING: Poland. PARTICIPANTS: Of the cohort of 1400 who self-prese...

Descripción completa

Detalles Bibliográficos
Autores principales: Słomko, Joanna, Newton, Julia L, Kujawski, Sławomir, Tafil-Klawe, Małgorzata, Klawe, Jacek, Staines, Donald, Marshall-Gradisnik, Sonya, Zalewski, Pawel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429942/
https://www.ncbi.nlm.nih.gov/pubmed/30850404
http://dx.doi.org/10.1136/bmjopen-2018-023955
_version_ 1783405697260584960
author Słomko, Joanna
Newton, Julia L
Kujawski, Sławomir
Tafil-Klawe, Małgorzata
Klawe, Jacek
Staines, Donald
Marshall-Gradisnik, Sonya
Zalewski, Pawel
author_facet Słomko, Joanna
Newton, Julia L
Kujawski, Sławomir
Tafil-Klawe, Małgorzata
Klawe, Jacek
Staines, Donald
Marshall-Gradisnik, Sonya
Zalewski, Pawel
author_sort Słomko, Joanna
collection PubMed
description OBJECTIVES: The aim of this study was to estimate the prevalence of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and describe illness characteristics in a community population in Poland. Design: cross-sectional study. SETTING: Poland. PARTICIPANTS: Of the cohort of 1400 who self-presented with fatigue only 69 subsequently were confirmed as having CFS/ME using the Fukuda criteria. MAIN OUTCOME MEASURES: Participants completed the following screening symptom assessment tools: Chalder Fatigue Scale, Hospital Anxiety and Depression Scale (HADS), Epworth Sleepiness Scale (ESS), Composite Autonomic Symptom Score 31 (COMPASS 31), Quality of Life Scale (QOLS). Haemodynamic and autonomic parameters were automatically measured at rest with a Task Force Monitor. RESULTS: In 1308, from 1400 (93%) individuals who identified themselves as fatigued, recognised chronic conditions were identified, for example, neurological (n=280, 21.5%), neurodegenerative (n=200, 15%), psychiatric (n=654, 50%) and immunologic (n=174, 13.5%) disorders. The remaining 69 participants (mean age 38.3±8.5) met the Fukuda defintion for CFS/ME and had baseline objective assessment. The majority had experienced symptoms for over 2 years with 37% having symptoms for 2–5 years and 21.7% for more than 10 years. The COMPASS 31 indicated that 50% have symptoms consistent with orthostatic intolerance. About 43/69 (62%) had Epworth sleepiness scores ≥10, ie, consistent with excessive daytime sleepiness, 26/69 (38%) had significant anxiety and 22/69 (32%) depression measured by HADS A & D. Quality of life is significantly impaired in those with Fukuda criteria CFS (QLS score 64±11) with significant negative relationships between quality of life and fatigue (p<0.0001), anxiety (p=0.0009), depression (p<0.0001) and autonomic symptoms (p=0.04). CONCLUSION: This is the first study to summarise illness characteristics of Polish CFS/ME patients. Our study has confirmed that fatigue is a common and under-recognised symptom affecting the Polish population.
format Online
Article
Text
id pubmed-6429942
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher BMJ Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-64299422019-04-05 Prevalence and characteristics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in Poland: a cross-sectional study Słomko, Joanna Newton, Julia L Kujawski, Sławomir Tafil-Klawe, Małgorzata Klawe, Jacek Staines, Donald Marshall-Gradisnik, Sonya Zalewski, Pawel BMJ Open Public Health OBJECTIVES: The aim of this study was to estimate the prevalence of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and describe illness characteristics in a community population in Poland. Design: cross-sectional study. SETTING: Poland. PARTICIPANTS: Of the cohort of 1400 who self-presented with fatigue only 69 subsequently were confirmed as having CFS/ME using the Fukuda criteria. MAIN OUTCOME MEASURES: Participants completed the following screening symptom assessment tools: Chalder Fatigue Scale, Hospital Anxiety and Depression Scale (HADS), Epworth Sleepiness Scale (ESS), Composite Autonomic Symptom Score 31 (COMPASS 31), Quality of Life Scale (QOLS). Haemodynamic and autonomic parameters were automatically measured at rest with a Task Force Monitor. RESULTS: In 1308, from 1400 (93%) individuals who identified themselves as fatigued, recognised chronic conditions were identified, for example, neurological (n=280, 21.5%), neurodegenerative (n=200, 15%), psychiatric (n=654, 50%) and immunologic (n=174, 13.5%) disorders. The remaining 69 participants (mean age 38.3±8.5) met the Fukuda defintion for CFS/ME and had baseline objective assessment. The majority had experienced symptoms for over 2 years with 37% having symptoms for 2–5 years and 21.7% for more than 10 years. The COMPASS 31 indicated that 50% have symptoms consistent with orthostatic intolerance. About 43/69 (62%) had Epworth sleepiness scores ≥10, ie, consistent with excessive daytime sleepiness, 26/69 (38%) had significant anxiety and 22/69 (32%) depression measured by HADS A & D. Quality of life is significantly impaired in those with Fukuda criteria CFS (QLS score 64±11) with significant negative relationships between quality of life and fatigue (p<0.0001), anxiety (p=0.0009), depression (p<0.0001) and autonomic symptoms (p=0.04). CONCLUSION: This is the first study to summarise illness characteristics of Polish CFS/ME patients. Our study has confirmed that fatigue is a common and under-recognised symptom affecting the Polish population. BMJ Publishing Group 2019-03-07 /pmc/articles/PMC6429942/ /pubmed/30850404 http://dx.doi.org/10.1136/bmjopen-2018-023955 Text en © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Public Health
Słomko, Joanna
Newton, Julia L
Kujawski, Sławomir
Tafil-Klawe, Małgorzata
Klawe, Jacek
Staines, Donald
Marshall-Gradisnik, Sonya
Zalewski, Pawel
Prevalence and characteristics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in Poland: a cross-sectional study
title Prevalence and characteristics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in Poland: a cross-sectional study
title_full Prevalence and characteristics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in Poland: a cross-sectional study
title_fullStr Prevalence and characteristics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in Poland: a cross-sectional study
title_full_unstemmed Prevalence and characteristics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in Poland: a cross-sectional study
title_short Prevalence and characteristics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in Poland: a cross-sectional study
title_sort prevalence and characteristics of chronic fatigue syndrome/myalgic encephalomyelitis (cfs/me) in poland: a cross-sectional study
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429942/
https://www.ncbi.nlm.nih.gov/pubmed/30850404
http://dx.doi.org/10.1136/bmjopen-2018-023955
work_keys_str_mv AT słomkojoanna prevalenceandcharacteristicsofchronicfatiguesyndromemyalgicencephalomyelitiscfsmeinpolandacrosssectionalstudy
AT newtonjulial prevalenceandcharacteristicsofchronicfatiguesyndromemyalgicencephalomyelitiscfsmeinpolandacrosssectionalstudy
AT kujawskisławomir prevalenceandcharacteristicsofchronicfatiguesyndromemyalgicencephalomyelitiscfsmeinpolandacrosssectionalstudy
AT tafilklawemałgorzata prevalenceandcharacteristicsofchronicfatiguesyndromemyalgicencephalomyelitiscfsmeinpolandacrosssectionalstudy
AT klawejacek prevalenceandcharacteristicsofchronicfatiguesyndromemyalgicencephalomyelitiscfsmeinpolandacrosssectionalstudy
AT stainesdonald prevalenceandcharacteristicsofchronicfatiguesyndromemyalgicencephalomyelitiscfsmeinpolandacrosssectionalstudy
AT marshallgradisniksonya prevalenceandcharacteristicsofchronicfatiguesyndromemyalgicencephalomyelitiscfsmeinpolandacrosssectionalstudy
AT zalewskipawel prevalenceandcharacteristicsofchronicfatiguesyndromemyalgicencephalomyelitiscfsmeinpolandacrosssectionalstudy