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Intraperitoneal delivery of acetate-encapsulated liposomal nanoparticles for neuroprotection of the penumbra in a rat model of ischemic stroke

BACKGROUND: Ischemic stroke is a devastating condition, with metabolic derangement and persistent inflammation enhancing the initial insult of ischaemia. Recombinant tissue plasminogen remains the only effective treatment but limited as therapy must commence soon after the onset of symptoms. PURPOSE...

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Detalles Bibliográficos
Autores principales: So, Po-Wah, Ekonomou, Antigoni, Galley, Kim, Brody, Leigh, Sahuri-Arisoylu, Meliz, Rattray, Ivan, Cash, Diana, Bell, Jimmy D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430000/
https://www.ncbi.nlm.nih.gov/pubmed/30936698
http://dx.doi.org/10.2147/IJN.S193965