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Intraperitoneal delivery of acetate-encapsulated liposomal nanoparticles for neuroprotection of the penumbra in a rat model of ischemic stroke
BACKGROUND: Ischemic stroke is a devastating condition, with metabolic derangement and persistent inflammation enhancing the initial insult of ischaemia. Recombinant tissue plasminogen remains the only effective treatment but limited as therapy must commence soon after the onset of symptoms. PURPOSE...
Autores principales: | So, Po-Wah, Ekonomou, Antigoni, Galley, Kim, Brody, Leigh, Sahuri-Arisoylu, Meliz, Rattray, Ivan, Cash, Diana, Bell, Jimmy D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430000/ https://www.ncbi.nlm.nih.gov/pubmed/30936698 http://dx.doi.org/10.2147/IJN.S193965 |
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