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Brief Report: A Differential Transcriptomic Profile of Ex Vivo Expanded Adult Human Hematopoietic Stem Cells Empowers Them for Engraftment Better than Their Surface Phenotype

Transplantation of small cord blood (CB) units, or of autologous ex vivo‐genetically modified adult hematopoietic stem cells (HSC), face the common challenge of suboptimal HSC doses for infusion and impaired engraftment of the transplanted cells. Ex vivo expansion of HSCs, using either cell‐based co...

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Detalles Bibliográficos
Autores principales: Psatha, Nikoletta, Georgolopoulos, Grigorios, Phelps, Susan, Papayannopoulou, Thalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430062/
https://www.ncbi.nlm.nih.gov/pubmed/28801972
http://dx.doi.org/10.1002/sctm.17-0048