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Disseminated tuberculosis with severe immune thrombocytopenia

Immune thrombocytopenia is an autoimmune condition with increased platelet destruction. Immune thrombocytopenic purpura is an uncommon and rare manifestation of tuberculosis. A search of the literature available on TB-associated ITP identified only around 50 cases published between 1964 and 2016. We...

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Autores principales: Rama Krishna, Malla, Gottam, Uma Sri, Mahendra, Nagendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430074/
https://www.ncbi.nlm.nih.gov/pubmed/30949428
http://dx.doi.org/10.1016/j.rmcr.2019.02.013
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author Rama Krishna, Malla
Gottam, Uma Sri
Mahendra, Nagendra
author_facet Rama Krishna, Malla
Gottam, Uma Sri
Mahendra, Nagendra
author_sort Rama Krishna, Malla
collection PubMed
description Immune thrombocytopenia is an autoimmune condition with increased platelet destruction. Immune thrombocytopenic purpura is an uncommon and rare manifestation of tuberculosis. A search of the literature available on TB-associated ITP identified only around 50 cases published between 1964 and 2016. We present an uncommon and interesting case of severe isolated immune thrombocytopenia secondary to bilateral tubercular cervical lymphadenopathy and pott's spine in 26 year old Indian male. Due to severe thrombocytopenia patient was managed with IVIg and steroids along with anti tubercular therapy. Early diagnosis and treatment with Anti tubercular therapy is important for effective control of bleeding manifestations.
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spelling pubmed-64300742019-04-04 Disseminated tuberculosis with severe immune thrombocytopenia Rama Krishna, Malla Gottam, Uma Sri Mahendra, Nagendra Respir Med Case Rep Article Immune thrombocytopenia is an autoimmune condition with increased platelet destruction. Immune thrombocytopenic purpura is an uncommon and rare manifestation of tuberculosis. A search of the literature available on TB-associated ITP identified only around 50 cases published between 1964 and 2016. We present an uncommon and interesting case of severe isolated immune thrombocytopenia secondary to bilateral tubercular cervical lymphadenopathy and pott's spine in 26 year old Indian male. Due to severe thrombocytopenia patient was managed with IVIg and steroids along with anti tubercular therapy. Early diagnosis and treatment with Anti tubercular therapy is important for effective control of bleeding manifestations. Elsevier 2019-02-25 /pmc/articles/PMC6430074/ /pubmed/30949428 http://dx.doi.org/10.1016/j.rmcr.2019.02.013 Text en © 2019 The Authors. Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Rama Krishna, Malla
Gottam, Uma Sri
Mahendra, Nagendra
Disseminated tuberculosis with severe immune thrombocytopenia
title Disseminated tuberculosis with severe immune thrombocytopenia
title_full Disseminated tuberculosis with severe immune thrombocytopenia
title_fullStr Disseminated tuberculosis with severe immune thrombocytopenia
title_full_unstemmed Disseminated tuberculosis with severe immune thrombocytopenia
title_short Disseminated tuberculosis with severe immune thrombocytopenia
title_sort disseminated tuberculosis with severe immune thrombocytopenia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430074/
https://www.ncbi.nlm.nih.gov/pubmed/30949428
http://dx.doi.org/10.1016/j.rmcr.2019.02.013
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AT mahendranagendra disseminatedtuberculosiswithsevereimmunethrombocytopenia