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Disseminated tuberculosis with severe immune thrombocytopenia
Immune thrombocytopenia is an autoimmune condition with increased platelet destruction. Immune thrombocytopenic purpura is an uncommon and rare manifestation of tuberculosis. A search of the literature available on TB-associated ITP identified only around 50 cases published between 1964 and 2016. We...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430074/ https://www.ncbi.nlm.nih.gov/pubmed/30949428 http://dx.doi.org/10.1016/j.rmcr.2019.02.013 |
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author | Rama Krishna, Malla Gottam, Uma Sri Mahendra, Nagendra |
author_facet | Rama Krishna, Malla Gottam, Uma Sri Mahendra, Nagendra |
author_sort | Rama Krishna, Malla |
collection | PubMed |
description | Immune thrombocytopenia is an autoimmune condition with increased platelet destruction. Immune thrombocytopenic purpura is an uncommon and rare manifestation of tuberculosis. A search of the literature available on TB-associated ITP identified only around 50 cases published between 1964 and 2016. We present an uncommon and interesting case of severe isolated immune thrombocytopenia secondary to bilateral tubercular cervical lymphadenopathy and pott's spine in 26 year old Indian male. Due to severe thrombocytopenia patient was managed with IVIg and steroids along with anti tubercular therapy. Early diagnosis and treatment with Anti tubercular therapy is important for effective control of bleeding manifestations. |
format | Online Article Text |
id | pubmed-6430074 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-64300742019-04-04 Disseminated tuberculosis with severe immune thrombocytopenia Rama Krishna, Malla Gottam, Uma Sri Mahendra, Nagendra Respir Med Case Rep Article Immune thrombocytopenia is an autoimmune condition with increased platelet destruction. Immune thrombocytopenic purpura is an uncommon and rare manifestation of tuberculosis. A search of the literature available on TB-associated ITP identified only around 50 cases published between 1964 and 2016. We present an uncommon and interesting case of severe isolated immune thrombocytopenia secondary to bilateral tubercular cervical lymphadenopathy and pott's spine in 26 year old Indian male. Due to severe thrombocytopenia patient was managed with IVIg and steroids along with anti tubercular therapy. Early diagnosis and treatment with Anti tubercular therapy is important for effective control of bleeding manifestations. Elsevier 2019-02-25 /pmc/articles/PMC6430074/ /pubmed/30949428 http://dx.doi.org/10.1016/j.rmcr.2019.02.013 Text en © 2019 The Authors. Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Rama Krishna, Malla Gottam, Uma Sri Mahendra, Nagendra Disseminated tuberculosis with severe immune thrombocytopenia |
title | Disseminated tuberculosis with severe immune thrombocytopenia |
title_full | Disseminated tuberculosis with severe immune thrombocytopenia |
title_fullStr | Disseminated tuberculosis with severe immune thrombocytopenia |
title_full_unstemmed | Disseminated tuberculosis with severe immune thrombocytopenia |
title_short | Disseminated tuberculosis with severe immune thrombocytopenia |
title_sort | disseminated tuberculosis with severe immune thrombocytopenia |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430074/ https://www.ncbi.nlm.nih.gov/pubmed/30949428 http://dx.doi.org/10.1016/j.rmcr.2019.02.013 |
work_keys_str_mv | AT ramakrishnamalla disseminatedtuberculosiswithsevereimmunethrombocytopenia AT gottamumasri disseminatedtuberculosiswithsevereimmunethrombocytopenia AT mahendranagendra disseminatedtuberculosiswithsevereimmunethrombocytopenia |