Discovery of an Indirubin Derivative as a Novel c-Met Kinase Inhibitor with In Vitro Anti-Tumor Effects

The c-Met protein is a receptor tyrosine kinase involved in cell growth, proliferation, survival, and angiogenesis of several human tumors. Overexpression of c-Met has been found in gastric cancers and correlated with a poor prognosis. Indirubin is the active component of Danggui Longhui Wan, which...

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Detalles Bibliográficos
Autores principales: Ndolo, Karyn Muzinga, An, Su Jin, Park, Kyeong Ryang, Lee, Hyo Jeong, Yoon, Kyoung Bin, Kim, Yong-Chul, Han, Sun-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430219/
https://www.ncbi.nlm.nih.gov/pubmed/30060294
http://dx.doi.org/10.4062/biomolther.2018.091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430219/
https://www.ncbi.nlm.nih.gov/pubmed/30060294
http://dx.doi.org/10.4062/biomolther.2018.091

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