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Genome Sequencing of Polydrug-, Multidrug-, and Extensively Drug-Resistant Mycobacterium tuberculosis Strains from South India

The genomes of 16 clinical Mycobacterium tuberculosis isolates were subjected to whole-genome sequencing to identify mutations related to resistance to one or more anti-Mycobacterium drugs. The sequence data will help in understanding the genomic characteristics of M. tuberculosis isolates and their...

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Detalles Bibliográficos
Autores principales: Shanmugam, Sivakumar, Kumar, Narender, Nair, Dina, Natrajan, Mohan, Tripathy, Srikanth Prasad, Peacock, Sharon J., Swaminathan, Soumya, Ranganathan, Uma Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430323/
https://www.ncbi.nlm.nih.gov/pubmed/30938706
http://dx.doi.org/10.1128/MRA.01388-18
Descripción
Sumario:The genomes of 16 clinical Mycobacterium tuberculosis isolates were subjected to whole-genome sequencing to identify mutations related to resistance to one or more anti-Mycobacterium drugs. The sequence data will help in understanding the genomic characteristics of M. tuberculosis isolates and their resistance mutations prevalent in South India.