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Resveratrol enhances the chemotherapeutic response and reverses the stemness induced by gemcitabine in pancreatic cancer cells via targeting SREBP1

OBJECTIVES: Gemcitabine is a standard treatment for advanced pancreatic cancer patients but can cause chemoresistance during treatment. The chemoresistant cells have features of cancer stem cells (CSCs). Resveratrol has been reported to overcome the resistance induced by gemcitabine. However, the me...

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Detalles Bibliográficos
Autores principales: Zhou, Cancan, Qian, Weikun, Ma, Jiguang, Cheng, Liang, Jiang, Zhengdong, Yan, Bin, Li, Jie, Duan, Wanxing, Sun, Liankang, Cao, Junyu, Wang, Fengfei, Wu, Erxi, Wu, Zheng, Ma, Qingyong, Li, Xuqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430460/
https://www.ncbi.nlm.nih.gov/pubmed/30341797
http://dx.doi.org/10.1111/cpr.12514