Single-molecule polarization microscopy of DNA intercalators sheds light on the structure of S-DNA

DNA structural transitions facilitate genomic processes, mediate drug-DNA interactions, and inform the development of emerging DNA-based biotechnology such as programmable materials and DNA origami. While some features of DNA conformational changes are well characterized, fundamental information suc...

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Detalles Bibliográficos
Autores principales: Backer, Adam S., Biebricher, Andreas S., King, Graeme A., Wuite, Gijs J. L., Heller, Iddo, Peterman, Erwin J. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430628/
https://www.ncbi.nlm.nih.gov/pubmed/30915395
http://dx.doi.org/10.1126/sciadv.aav1083

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