A chemoproteomic portrait of the oncometabolite fumarate

Hereditary cancer disorders often provide an important window into novel mechanisms supporting tumor growth. Understanding these mechanisms thus represents a vital goal. Towards this goal, here we report a chemoproteomic map of fumarate, a covalent oncometabolite whose accumulation marks the genetic...

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Detalles Bibliográficos
Autores principales: Kulkarni, Rhushikesh A., Bak, Daniel W., Wei, Darmood, Bergholtz, Sarah E., Briney, Chloe A., Shrimp, Jonathan H., Alpsoy, Aktan, Thorpe, Abigail L., Bavari, Arissa E., Crooks, Daniel R., Levy, Michaella, Florens, Laurence, Washburn, Michael P., Frizzell, Norma, Dykhuizen, Emily C., Weerapana, Eranthie, Linehan, W. Marston, Meier, Jordan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430658/
https://www.ncbi.nlm.nih.gov/pubmed/30718813
http://dx.doi.org/10.1038/s41589-018-0217-y

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