Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux

Triple-negative breast cancer (TNBC), the most aggressive breast cancer subtype, currently lacks effective targeted therapy options. Eicosapentaenoic acid (EPA), an omega-3 fatty acid and constituent of fish oil, is a common supplement with anti-inflammatory properties. Although it is not a mainstre...

Descripción completa

Detalles Bibliográficos
Autores principales: Torres-Adorno, Angie M., Vitrac, Heidi, Qi, Yuan, Tan, Lin, Levental, Kandice R., Fan, Yang-Yi, Yang, Peiying, Chapkin, Robert S., Eckhardt, Bedrich L., Ueno, Naoto T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430703/
https://www.ncbi.nlm.nih.gov/pubmed/30459358
http://dx.doi.org/10.1038/s41388-018-0569-5

Ejemplares similares

Ejemplares similares