Selective binding of a toxin and phosphatidylinositides to a mammalian potassium channel

G-protein-gated inward rectifying potassium channels (GIRKs) require G(βγ) subunits and phosphorylated phosphatidylinositides (PIPs) for gating. Although studies have provided insight into these interactions, the mechanism of how these events are modulated by G(βγ) and the binding affinity between P...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yang, LoCaste, Catherine E., Liu, Wen, Poltash, Michael L., Russell, David H., Laganowsky, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430785/
https://www.ncbi.nlm.nih.gov/pubmed/30902995
http://dx.doi.org/10.1038/s41467-019-09333-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430785/
https://www.ncbi.nlm.nih.gov/pubmed/30902995
http://dx.doi.org/10.1038/s41467-019-09333-4

Ejemplares similares