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Selective binding of a toxin and phosphatidylinositides to a mammalian potassium channel
G-protein-gated inward rectifying potassium channels (GIRKs) require G(βγ) subunits and phosphorylated phosphatidylinositides (PIPs) for gating. Although studies have provided insight into these interactions, the mechanism of how these events are modulated by G(βγ) and the binding affinity between P...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430785/ https://www.ncbi.nlm.nih.gov/pubmed/30902995 http://dx.doi.org/10.1038/s41467-019-09333-4 |