Medication‐related osteonecrosis of the jaw after long‐term bisphosphonate treatment in a cat

A 12‐year‐old, neutered female, domestic medium hair cat was evaluated for a nonhealing, oral mucosal ulceration. The cat had a history of idiopathic hypercalcemia that had been treated with a bisphosphonate for 41 months. Oral examination identified exposed maxillary bone adjacent to a previous ext...

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Autores principales: Larson, Melinda J., Oakes, Ashley B., Epperson, Ember, Chew, Dennis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
SMALL ANIMAL
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430911/
https://www.ncbi.nlm.nih.gov/pubmed/30663796
http://dx.doi.org/10.1111/jvim.15409
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author Larson, Melinda J.
Oakes, Ashley B.
Epperson, Ember
Chew, Dennis J.
author_facet Larson, Melinda J.
Oakes, Ashley B.
Epperson, Ember
Chew, Dennis J.
author_sort Larson, Melinda J.
collection PubMed
description A 12‐year‐old, neutered female, domestic medium hair cat was evaluated for a nonhealing, oral mucosal ulceration. The cat had a history of idiopathic hypercalcemia that had been treated with a bisphosphonate for 41 months. Oral examination identified exposed maxillary bone adjacent to a previous extraction site. Histopathology of the exposed bone and associated mucosa was most consistent with medication‐related osteonecrosis of the jaw. Treatment involved both medical and surgical interventions. Oral mucosal healing occurred after 6 months of treatment.
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spelling pubmed-64309112019-04-04 Medication‐related osteonecrosis of the jaw after long‐term bisphosphonate treatment in a cat Larson, Melinda J. Oakes, Ashley B. Epperson, Ember Chew, Dennis J. J Vet Intern Med SMALL ANIMAL A 12‐year‐old, neutered female, domestic medium hair cat was evaluated for a nonhealing, oral mucosal ulceration. The cat had a history of idiopathic hypercalcemia that had been treated with a bisphosphonate for 41 months. Oral examination identified exposed maxillary bone adjacent to a previous extraction site. Histopathology of the exposed bone and associated mucosa was most consistent with medication‐related osteonecrosis of the jaw. Treatment involved both medical and surgical interventions. Oral mucosal healing occurred after 6 months of treatment. John Wiley and Sons Inc. 2019-01-21 2019 /pmc/articles/PMC6430911/ /pubmed/30663796 http://dx.doi.org/10.1111/jvim.15409 Text en © 2019 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle SMALL ANIMAL
Larson, Melinda J.
Oakes, Ashley B.
Epperson, Ember
Chew, Dennis J.
Medication‐related osteonecrosis of the jaw after long‐term bisphosphonate treatment in a cat
title Medication‐related osteonecrosis of the jaw after long‐term bisphosphonate treatment in a cat
title_full Medication‐related osteonecrosis of the jaw after long‐term bisphosphonate treatment in a cat
title_fullStr Medication‐related osteonecrosis of the jaw after long‐term bisphosphonate treatment in a cat
title_full_unstemmed Medication‐related osteonecrosis of the jaw after long‐term bisphosphonate treatment in a cat
title_short Medication‐related osteonecrosis of the jaw after long‐term bisphosphonate treatment in a cat
title_sort medication‐related osteonecrosis of the jaw after long‐term bisphosphonate treatment in a cat
topic SMALL ANIMAL
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430911/
https://www.ncbi.nlm.nih.gov/pubmed/30663796
http://dx.doi.org/10.1111/jvim.15409
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