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Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability

BACKGROUND: Epithelial-mesenchymal transition (EMT) may be one of the reasons for the failure in some clinical trials regarding histone deacetylase inhibitors (HDACIs)-treated solid tumors. We investigated the effects of a pan-HDACI trichostatin A (TSA) on the proliferation and EMT of nasopharyngeal...

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Detalles Bibliográficos
Autores principales:	Shen, Zhihua, Liao, Xiaomin, Shao, Zhongming, Feng, Muyin, Yuan, Jianling, Wang, Sisi, Gan, Siyuan, Ha, Yanping, He, Zhiwei, Jie, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431036/ https://www.ncbi.nlm.nih.gov/pubmed/30902084 http://dx.doi.org/10.1186/s12885-019-5482-y

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