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Pioglitazone strengthen therapeutic effect of adipose-derived regenerative cells against ischemic cardiomyopathy through enhanced expression of adiponectin and modulation of macrophage phenotype
BACKGROUND: The efficacy of cell transplantation in heart failure is reportedly modest, but adjuvant drugs combined with cell therapy may improve this efficacy. Peroxisome proliferator-activated receptor (PPAR)γ, one of the hypoglycemic medicine for diabetes mellitus, reportedly enhances cytokine pr...
Autores principales: | Mori, Daisuke, Miyagawa, Shigeru, Matsuura, Ryohei, Sougawa, Nagako, Fukushima, Satsuki, Ueno, Takayoshi, Toda, Koichi, Kuratani, Toru, Tomita, Koichi, Maeda, Norikazu, Shimomura, Iichiro, Sawa, Yoshiki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431071/ https://www.ncbi.nlm.nih.gov/pubmed/30902059 http://dx.doi.org/10.1186/s12933-019-0829-x |
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