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Allopurinol potentiates the hepatoprotective effect of metformin and vitamin E in fructose-induced fatty liver in rats
AIM OF THE STUDY: Non-alcoholic fatty liver disease (NAFLD) is a challenging health problem. Hyperuricemia is a key player in the pathogenesis of NAFLD. This study investigated the effect of allopurinol (uric acid synthesis inhibitor) in combination with metformin and vitamin E in prevention of fruc...
Autores principales: | Khalaf, Hanaa Mohamed, Ibrahim, Mohamed Abdellah, Amin, Entesar Farghaly, Abdel-tawab Ibrahim, Salwa, Abdel-Wahab, Soha, Fouad, Yasser Mahrous |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431087/ https://www.ncbi.nlm.nih.gov/pubmed/30915409 http://dx.doi.org/10.5114/ceh.2019.83159 |
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